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Electronic marketplace-to-marketplace alliances: emerging trends and strategic rationales
The electronic marketplace domain has recently witnessed the joining together of a number of previously independent marketplaces and the formation of collaborative alliances between others. This study seeks to determine the nature or type of cooperative arrangements or alliances that are currently being forged between electronic marketplaces, and the strategic rationale that is leading to this observed alliance formation. The findings of the study are based upon an examination of statements made to the press by marketplaces undertaking strategic alliances. This published data was supplemented with face-to-face interviews with managers at three relevant electronic marketplaces. Three distinct types of alliance are observed; the merger between previously separate marketplaces, the acquisition of one marketplace by another and the formation of an interoperability agreement between two marketplaces. Three rationales for alliance formation were observed: an increase in the number of buyers or suppliers in a given market sector that can access the marketplace (an increase in scale of operations), an increase in the breadth or depth of services that are offered to users of the marketplace (an increase in the scope of operations) and providing the ability to exchange information across multiple tiers of a supply chain. A broader discussion of the findings is given and suggestions for further research are made
Extremism propagation in social networks with hubs
One aspect of opinion change that has been of academic interest is the impact of people with extreme opinions (extremists) on opinion dynamics. An agent-based model has been used to study the role of small-world social network topologies on general opinion change in the presence of extremists. It has been found that opinion convergence to a single extreme occurs only when the average number of network connections for each individual is extremely high. Here, we extend the model to examine the effect of positively skewed degree distributions, in addition to small-world structures, on the types of opinion convergence that occur in the presence of extremists. We also examine what happens when extremist opinions are located on the well-connected nodes (hubs) created by the positively skewed distribution. We find that a positively skewed network topology encourages opinion convergence on a single extreme under a wider range of conditions than topologies whose degree distributions were not skewed. The importance of social position for social influence is highlighted by the result that, when positive extremists are placed on hubs, all population convergence is to the positive extreme even when there are twice as many negative extremists. Thus, our results have shown the importance of considering a positively skewed degree distribution, and in particular network hubs and social position, when examining extremist transmission
Multilevel Modular Mesocrystalline Organization in Red Coral
International audienceBiominerals can achieve complex shapes as aggregates of crystalline building blocks. In the red coral skeleton, we observe that these building blocks are arranged into eight hierarchical levels of similarly (but not identically) oriented modules. The modules in each hierarchical level assemble into larger units that comprise the next higher level of the hierarchy, and consist themselves of smaller, oriented modules. EBSD and TEM studies show that the degree of crystallographic misorientation between the building blocks decreases with decreasing module size. We observe this organization down to a few nm. Thus, the transition from imperfect crystallographic order at mm scale to nearly perfect single crystalline domains at nm scale is progressive. The concept of 'mesocrystal' involves the three-dimensional crystallographic organization of nanoparticles into a highly ordered mesostructure. We add to this concept the notion of 'multilevel modularity'. This modularity has potential implications for the origin of complex biomineral shapes in nature. A multilevel modular organization with small intermodular misorientations combines a simple construction scheme, ruled by crystallographic laws, with the possibility of complex shapes. If the observations we have made on red coral extend to other biominerals, long-range crystallographic order and interfaces at all scales may be key to how some biominerals achieve complex shapes adapted to the environment in which they grow
Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies
Background
Before introducing proteins from new or alternative dietary sources into the market, a compressive risk assessment including food allergic sensitization should be carried out in order to ensure their safety. We have recently proposed the adverse outcome pathway (AOP) concept to structure the current mechanistic understanding of the molecular and cellular pathways evidenced to drive IgE-mediated food allergies. This AOP framework offers the biological context to collect and structure existing in vitro methods and to identify missing assays to evaluate sensitizing potential of food proteins.
Scope and approach
In this review, we provide a state-of-the-art overview of available in vitro approaches for assessing the sensitizing potential of food proteins, including their strengths and limitations. These approaches are structured by their potential to evaluate the molecular initiating and key events driving food sensitization.
Key findings and conclusions
The application of the AOP framework offers the opportunity to anchor existing testing methods to specific building blocks of the AOP for food sensitization. In general, in vitro methods evaluating mechanisms involved in the innate immune response are easier to address than assays addressing the adaptive immune response due to the low precursor frequency of allergen-specific T and B cells. Novel ex vivo culture strategies may have the potential to become useful tools for investigating the sensitizing potential of food proteins. When applied in the context of an integrated testing strategy, the described approaches may reduce, if not replace, current animal testing approaches
Transport Properties near the z=2 Insulator-Superconductor Transition
We consider here the fluctuation conductivity near the point of the
insulator-superconductor transition in a system of regular Josephson junction
arrays in the presence of particle-hole asymmetry or equivalently homogeneous
charge frustration. The transition is characterised by the dynamic critical
exponent , opening the possibility of the perturbative
renormalization-group (RG) treatment. The quartic interaction in the
Ginzburg-Landau action and the coupling to the Ohmic heat bath, giving the
finite quasiparticle life-time, lead to the non-monotonic behavior of the dc
conductivity as a function of temperature in the leading logarithmic
approximation.Comment: Revised version for publication. To appear in PR
Herschel-ATLAS/GAMA: A difference between star formation rates in strong-line and weak-line radio galaxies
We have constructed a sample of radio-loud objects with optical spectroscopy from the Galaxy and Mass Assembly (GAMA) project over the Herschel Astrophysical Terahertz Large Area Survey (Herschel-ATLAS) Phase 1 fields. Classifying the radio sources in terms of their optical spectra, we find that strong-emission-line sources ('high-excitation radio galaxies') have, on average, a factor of ~4 higher 250-μm Herschel luminosity than weak-line ('lowexcitation') radio galaxies and are also more luminous than magnitude-matched radio-quiet galaxies at the same redshift. Using all five H-ATLAS bands, we show that this difference in luminosity between the emission-line classes arises mostly from a difference in the average dust temperature; strong-emission-line sources tend to have comparable dust masses to, but higher dust temperatures than, radio galaxies with weak emission lines. We interpret this as showing that radio galaxies with strong nuclear emission lines are much more likely to be associated with star formation in their host galaxy, although there is certainly not a one-to-one relationship between star formation and strong-line active galactic nuclei (AGN) activity. The strong-line sources are estimated to have star formation rates at least a factor of 3-4 higher than those in the weak-line objects. Our conclusion is consistent with earlier work, generally carried out using much smaller samples, and reinforces the general picture of high-excitation radio galaxies as being located in lower-mass, less evolved host galaxies than their low-excitation counterparts.Peer reviewe
Kasner and Mixmaster behavior in universes with equation of state w \ge 1
We consider cosmological models with a scalar field with equation of state
that contract towards a big crunch singularity, as in recent cyclic
and ekpyrotic scenarios. We show that chaotic mixmaster oscillations due to
anisotropy and curvature are suppressed, and the contraction is described by a
homogeneous and isotropic Friedmann equation if . We generalize the
results to theories where the scalar field couples to p-forms and show that
there exists a finite value of , depending on the p-forms, such that chaotic
oscillations are suppressed. We show that orbifold compactification also
contributes to suppressing chaotic behavior. In particular, chaos is avoided in
contracting heterotic M-theory models if at the crunch.Comment: 25 pages, 2 figures, minor changes, references adde
Sub-Poissonian statistics in order-to-chaos transition
We study the phenomena at the overlap of quantum chaos and nonclassical
statistics for the time-dependent model of nonlinear oscillator. It is shown in
the framework of Mandel Q-parameter and Wigner function that the statistics of
oscillatory excitation number is drastically changed in order-to chaos
transition. The essential improvement of sub-Poissonian statistics in
comparison with an analogous one for the standard model of driven anharmonic
oscillator is observed for the regular operational regime. It is shown that in
the chaotic regime the system exhibits the range of sub- and super-Poissonian
statistics which alternate one to other depending on time intervals. Unusual
dependence of the variance of oscillatory number on the external noise level
for the chaotic dynamics is observed.Comment: 9 pages, RevTeX, 14 figure
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